Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17115483 | 1.00 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C19RORCRORA | |
| SCHEMBL17115459 | 0.98 | RORC (0.42) | CYP1A2CYP2D6CYP2C19RORCRORA | |
| SCHEMBL17115382 | 0.95 | TSHR (0.42) | CYP1A2CYP2D6CYP2C19RORCRORA | |
| SCHEMBL17115366 | 0.91 | TSHR (0.40) | CYP1A2CYP2D6CYP2C19RORCRORA | |
| SCHEMBL19961421 | 0.90 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C19PDE10A | |
| SCHEMBL17115378 | 0.88 | TSHR (0.39) | RORCRORARORBTSHRHSD17B10 | |
| SCHEMBL17115466 | 0.87 | RORA (0.36) | CYP1A2CYP2D6CYP2C19RORCRORA | |
| SCHEMBL17115477 | 0.85 | HPGD (0.33) | CYP1A2CYP2D6CYP2C19RORCPTGER4 | |
| SCHEMBL17115482 | 0.85 | HPGD (0.33) | CYP1A2CYP2D6CYP2C19RORCPTGER4 | |
| SCHEMBL17705058 | 0.85 | TNKS (0.39) | RORCPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| WO-2015140073-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | DBF4, DDT, SLC43A3 | CYP1A2 1444/4885CYP2D6 944/4885CYP2C19 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.