Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191869 | 1.00 | LMNA (0.46) | LMNAMITFHSP90AA1ALDH1A1KMT2A | |
| SCHEMBL1711146 | 0.83 | MCL1 (0.55) | LMNAALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL21457693 | 0.78 | ADORA2A (0.60) | LMNAMITFHSP90AA1ALDH1A1KMT2A | |
| SCHEMBL7021269 | 0.78 | ADORA2A (0.60) | LMNAMITFHSP90AA1ALDH1A1KMT2A | |
| SCHEMBL7021270 | 0.78 | ADORA2A (0.60) | LMNAMITFHSP90AA1ALDH1A1KMT2A | |
| SCHEMBL801568 | 0.76 | ALDH1A1 (0.54) | HSP90AA1ALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL28436909 | 0.76 | MCL1 (0.60) | LMNAMITFHSP90AA1ALDH1A1KMT2A | |
| SCHEMBL28897442 | 0.76 | MCL1 (0.60) | LMNAMITFHSP90AA1ALDH1A1KMT2A | |
| SCHEMBL21457393 | 0.75 | ALDH1A1 (0.60) | LMNAMITFHSP90AA1ALDH1A1KMT2A | |
| SCHEMBL21457396 | 0.75 | ALDH1A1 (0.60) | LMNAMITFHSP90AA1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150510-B2 | Amino acid derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| EP-2345635-A1 | AMINO ACID DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110172442-A1 | AMINO ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172442-A1 | AMINO ACID DERIVATIVE | OPRL1, OPRK1, SLC1A1 | LMNA 4579/4885MITF 2828/4885HSP90AA1 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.