Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 12/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15709817 | 0.85 | AOC3 (0.38) | AOC3HRH3RXRAGRIN1GRIN2B | |
| SCHEMBL17115672 | 0.81 | AOC3 (0.46) | AOC3HRH3RORC | |
| SCHEMBL17115674 | 0.79 | LNPEP (0.38) | AOC3LRRK2 | |
| SCHEMBL17115658 | 0.77 | POLB (0.44) | RXRARORC | |
| SCHEMBL18860890 | 0.72 | GLS (0.58) | WNT3A | |
| SCHEMBL17115637 | 0.71 | AOC3 (0.38) | AOC3HRH3 | |
| SCHEMBL17115619 | 0.71 | CACNA1H (0.46) | AOC3WNT3A | |
| SCHEMBL25354279 | 0.71 | LIMK1 (0.35) | AOC3HRH3RXRAGRIN1GRIN2B | |
| SCHEMBL25352172 | 0.71 | LRRK2 (0.33) | AOC3RXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL18860888 | 0.70 | GLS (0.49) | HRH3WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015143340-A1 | COMPOUNDS AND THEIR METHODS OF USE | AGIOS PHARMACEUTICALS, INC. (US) | 2015-09-24 | — | — | WO | disclosed |