Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753021 | 0.87 | TRPA1 (0.40) | MEN1KMT2AMAP4K4KDM4EHTR1A | |
| SCHEMBL2750116 | 0.85 | HSPB1 (0.38) | MEN1KMT2AMAP4K4 | |
| SCHEMBL2753127 | 0.83 | HSPB1 (0.49) | MAP4K4 | |
| SCHEMBL2751987 | 0.81 | SLC6A2 (0.33) | MEN1KMT2AHTR1ASLC6A2 | |
| SCHEMBL693585 | 0.79 | KMT2A (0.49) | MEN1KMT2AMAP4K4ALDH1A1LMNA | |
| SCHEMBL2897755 | 0.79 | SMN1; SMN2 (0.55) | MEN1KMT2AMAP4K4MRGPRX1ALDH1A1 | |
| SCHEMBL7945557 | 0.79 | MRGPRX1 (0.39) | MEN1KMT2AMRGPRX1HTR1ASLC6A2 | |
| SCHEMBL2902921 | 0.77 | KDM4E (0.41) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL2901270 | 0.77 | MAP4K4 (0.46) | MAP4K4ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL16541082 | 0.76 | MEN1 (0.53) | MEN1KMT2AMAP4K4MRGPRX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146518-A | A kind of bruton's tyrosine kinase inhibitor intermediate and preparation method thereof | 苏州爱玛特生物科技有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2345328-A1 | COMPOSITION FOR AGRICULTURAL USE | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | H1-0, H1-3, H1-2 | MEN1 1798/4885KMT2A 1924/4885MAP4K4 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.