Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14755983 | 0.92 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4NPY5R | |
| SCHEMBL14848556 | 0.92 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4ALDH1A1 | |
| SCHEMBL13803220 | 0.88 | TSPO (0.38) | KDM4EATML3MBTL1PTGER4ALDH1A1 | |
| SCHEMBL15137920 | 0.88 | PTGER4 (0.36) | KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL14848553 | 0.88 | KDM4E (0.42) | KDM4EATML3MBTL1PTGER4ALDH1A1 | |
| SCHEMBL13872335 | 0.87 | MCL1 (0.31) | KDM4EATML3MBTL1PTGER4ALDH1A1 | |
| SCHEMBL14848622 | 0.87 | NLRP3 (0.32) | KDM4EATML3MBTL1PTGER4ALDH1A1 | |
| SCHEMBL17264012 | 0.86 | KDM4E (0.38) | KDM4EATML3MBTL1 | |
| SCHEMBL20349159 | 0.86 | KDM4E (0.40) | KDM4EATML3MBTL1PTGER4ALDH1A1 | |
| SCHEMBL9920632 | 0.85 | KDM4E (0.41) | KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015142040-A1 | ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2015-09-24 | — | — | WO | disclosed |