SCHEMBL17119002

SCHEMBL17119002

CCC1=C(C)/C(=C/c2ccc(C(C)C)cc2)c2ccc(OC)cc21

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RXRA P19793 7/20 0.63
PPARG P37231 3/20 0.43
LCK P06239 2/20 0.43
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
CSNK2A3 Q8NEV1 1/20 0.40
PRKACA P17612 1/20 0.39
PRKACG P22612 1/20 0.39
PRKACB P22694 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12181845 0.86 RXRA (0.80) RXRAPPARG
SCHEMBL30389970 0.86 RXRA (0.80) RXRAPPARG
SCHEMBL18697015 0.82 RXRA (0.74) RXRAPPARG
SCHEMBL30389830 0.82 RXRA (0.74) RXRAPPARG
SCHEMBL29068250 0.78 RXRA (1.00) RXRAPPARGCSNK2A2CSNK2BCSNK2A1
SCHEMBL17119516 0.78 RXRA (1.00) RXRAPPARGCSNK2A2CSNK2BCSNK2A1
SCHEMBL30390283 0.78 RXRA (1.00) RXRAPPARGCSNK2A2CSNK2BCSNK2A1
SCHEMBL19542342 0.76 RXRA (0.81) RXRAPPARGCSNK2A2CSNK2BCSNK2A1
SCHEMBL8154646 0.76 RXRA (0.44) RXRAPPARGLCKPRKACAPRKACG
SCHEMBL8154649 0.76 RXRA (0.44) RXRAPPARGLCKPRKACAPRKACG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150266842-A1 METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY US ARMY, SECRETARY OF THE ARMY 2015-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266842-A1 METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY RXRG, RXRB, RXRA RXRA 3/4885PPARG 43/4885LCK 3897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.