Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 13/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712069 | 0.80 | QPCT (0.39) | QPCT | |
| SCHEMBL583358 | 0.78 | QPCT (0.37) | QPCTIDH1PIK3CAMTORHDAC1 | |
| SCHEMBL1223966 | 0.78 | CALML3 (0.45) | — | |
| SCHEMBL8251549 | 0.78 | MAPT (0.39) | QPCTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL8259871 | 0.77 | CCR1 (0.41) | CYP1A2CYP3A4CYP2C19GFERCCR1 | |
| SCHEMBL584451 | 0.72 | PIK3CA (0.42) | QPCTPIK3CAMTORHDAC1HDAC8 | |
| SCHEMBL3198341 | 0.69 | QPCT (0.32) | QPCT | |
| SCHEMBL15873986 | 0.67 | DUT (0.40) | — | |
| SCHEMBL8256262 | 0.65 | PIK3CA (0.37) | QPCTIDH1PIK3CAMTORHDAC1 | |
| SCHEMBL13862087 | 0.65 | PIK3CA (0.39) | QPCTIDH1PIK3CAMTORHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344495-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010041194-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-15 | — | — | WO | disclosed |