Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 12/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584451 | 0.81 | PIK3CA (0.42) | QPCTPIK3CAMTORHDAC1HDAC8 | |
| SCHEMBL1711947 | 0.78 | QPCT (0.38) | QPCTPIK3CAMTORHDAC1HDAC8 | |
| SCHEMBL3198341 | 0.78 | QPCT (0.32) | QPCT | |
| SCHEMBL542136 | 0.77 | CALML3 (0.47) | — | |
| SCHEMBL711710 | 0.77 | GPR119 (0.41) | QPCT | |
| SCHEMBL3206967 | 0.73 | QPCT (0.33) | QPCTIDH1 | |
| SCHEMBL8251549 | 0.71 | MAPT (0.39) | QPCTPIK3CAMTORIDH1 | |
| SCHEMBL8256262 | 0.71 | PIK3CA (0.37) | QPCTPIK3CAMTORHDAC1HDAC8 | |
| SCHEMBL13862087 | 0.71 | PIK3CA (0.39) | QPCTPIK3CAMTORHDAC1HDAC8 | |
| SCHEMBL6021136 | 0.70 | NLRP3 (0.34) | QPCTPIK3CAMTORHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102217-B1 | 4- (2-OXO-OXAZOLIDIN-3YL)-PHENOXYMETHYLE DERIVATIVEAS AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |