Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | QPCT | Q16769 | 10/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583358 | 0.81 | QPCT (0.37) | PIK3CAMTORQPCTHDAC1HDAC8 | |
| SCHEMBL541588 | 0.80 | GRM2 (0.46) | S1PR5GRM2 | |
| SCHEMBL1711947 | 0.72 | QPCT (0.38) | PIK3CAMTORQPCTHDAC1HDAC8 | |
| SCHEMBL3198341 | 0.72 | QPCT (0.32) | QPCT | |
| SCHEMBL2108950 | 0.70 | S1PR5 (0.47) | S1PR5HDAC1HDAC8HDAC6GRM2 | |
| SCHEMBL3206967 | 0.69 | QPCT (0.33) | QPCT | |
| SCHEMBL9613257 | 0.69 | NAAA (0.45) | PIK3CAMTORS1PR5GRM2 | |
| SCHEMBL18202919 | 0.68 | GRM2 (0.49) | S1PR5GRM2KDM1A | |
| SCHEMBL541589 | 0.67 | S1PR5 (0.41) | S1PR5GRM2KDM1A | |
| SCHEMBL2519644 | 0.67 | FFAR1 (0.41) | S1PR5GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102217-B1 | 4- (2-OXO-OXAZOLIDIN-3YL)-PHENOXYMETHYLE DERIVATIVEAS AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |