Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17120701 | 0.89 | PRKCQ (0.42) | MCHR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17120730 | 0.89 | LMNA (0.50) | ALDH1A1KDM4EHPGDHSD17B10CHEK1 | |
| SCHEMBL17120729 | 0.83 | BACE1 (0.52) | MCHR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2975455 | 0.79 | FLT1 (0.57) | KDR | |
| SCHEMBL18221487 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10CHEK1 | |
| SCHEMBL19294027 | 0.79 | CHEK1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL19293993 | 0.79 | CHEK1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL19294021 | 0.78 | CHEK1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10CDK1 | |
| SCHEMBL2984893 | 0.78 | HRH3 (0.62) | — | |
| SCHEMBL2981464 | 0.78 | LTA4H (0.55) | MCHR1KDRCHRM1HTR2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015143185-A1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS (US) | 2015-09-24 | — | — | WO | disclosed |