Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.57 |
| ▸ | DRD3 | P35462 | 7/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16233625 | 0.81 | DRD2 (0.58) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL629616 | 0.81 | DRD2 (0.58) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL16233624 | 0.81 | DRD2 (0.58) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL7958191 | 0.79 | DRD2 (0.58) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL19900934 | 0.79 | DRD2 (0.87) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL16019151 | 0.79 | DRD2 (0.57) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL264631 | 0.79 | DRD2 (0.87) | DRD2DRD3CA1CA2ACHE | |
| Hydrochloric Acid SCHEMBL2991649 | 0.78 | DRD2 (0.84) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL8624827 | 0.77 | CA1 (0.64) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL8237115 | 0.77 | CA1 (0.64) | DRD2DRD3CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501678-B1 | ARYL-PYRIDINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS | NOVARTIS AG (CH) | 2015-09-23 | — | — | EP | disclosed |