Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.57 |
| ▸ | DRD3 | P35462 | 7/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485492 | 0.93 | DRD2 (0.66) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL14812350 | 0.84 | DRD2 (0.51) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL7958716 | 0.83 | CA1 (0.53) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL18264462 | 0.83 | FAAH (0.54) | CYP1A2CYP3A4CYP2C9CYP11B1CYP11B2 | |
| SCHEMBL16233625 | 0.81 | DRD2 (0.58) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL4529303 | 0.81 | CYP11B2 (0.54) | CYP1A2CYP3A4CYP2C9CYP11B1CYP11B2 | |
| SCHEMBL629616 | 0.81 | DRD2 (0.58) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL16233624 | 0.81 | DRD2 (0.58) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL6456941 | 0.79 | DRD2 (0.47) | DRD2DRD3CA1CA2ACHE | |
| SCHEMBL6456949 | 0.79 | DRD2 (0.47) | DRD2DRD3CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9044463-B2 | FSH receptor antagonists | MERCK SHARP & DOHME B.V. (NL) | 2015-06-02 | — | — | US | disclosed |
| US-20140256725-A1 | FSH RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME B.V. (NL) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256725-A1 | FSH RECEPTOR ANTAGONISTS | FSHR, GNRHR, LHCGR | DRD2 1262/4885DRD3 2031/4885CA1 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.