Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225847 | 1.00 | CYP2D6 (0.50) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL1964866 | 1.00 | CYP2D6 (0.50) | CYP2D6SRCLMNAMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL1967435 | 0.98 | KMT2A (0.48) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL10065853 | 0.88 | PTGS2 (0.58) | CYP2D6CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL2628427 | 0.84 | KMT2A (0.45) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL6275744 | 0.84 | KMT2A (0.45) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL6275948 | 0.84 | KMT2A (0.45) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL6966020 | 0.84 | KMT2A (0.45) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL6714743 | 0.83 | FOLH1 (0.55) | CYP2D6SRCLMNAKMT2ACHRM2 | |
| SCHEMBL5427932 | 0.83 | FOLH1 (0.55) | CYP2D6SRCLMNAKMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628680-B1 | MODULATION OF COMPLEMENT ACTIVITY | RA PHARMACEUTICALS INC (US) | 2021-09-08 | — | — | EP | claimed |
| CN-117362188-B | Synthesis method of alpha-substituted deuterated amino acid ester | 广州医科大学 | 2025-05-20 | — | — | CN | disclosed |
| EP-3998260-B1 | SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023164311-A2 | COMPOSITIONS AND METHODS OF TREATING AMYOTROPHIC LATERAL SCLEROSIS (ALS) AND RELATED DISORDERS | BIOINCEPT, LLC (US) | 2023-08-31 | — | — | WO | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| CN-113354635-B | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20230106002-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. | 2023-04-06 | — | — | US | disclosed |
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |
| EP-3998260-A1 | SGC STIMULATORS | Cyclerion Therapeutics, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |
| WO-2010029119-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | GALAPAGOS NV (BE) | 2010-03-18 | — | — | WO | disclosed |
| US-7238692-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-7169785-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169759-B1 | Tetrapeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-5583148-A | FUNGICIDE, BACTERICIDE AND ANTICARCINOGENIC AGENT | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0499376-A1 | Precipitation-induced asymmetric transformation of chiral alpha-amino acids and salts thereof | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-4723031-A | Processes for synthesizing substituted and unsubstituted aminoacetate esters | CHEVRON RESEARCH COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| US-4179511-A | Antibacterial 3-(5-tetrazolyl) penam compounds | PFIZER INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4143039-A | ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4115385-A | PENICILLINS | PFIZER INC. (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230106002-A1 | sGC STIMULATORS | PTGIS, CGAS, GUCY1A1 | CYP2D6 2096/4885SRC 2476/4885LMNA 3314/4885 |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | CYP2D6 4271/4885SRC 797/4885LMNA 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.