SCHEMBL17124137

SCHEMBL17124137

c1ccc(-n2c3ccc(-c4ccc(N(c5ccccn5)c5ccccn5)cc4)cc3c3cccnc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
FEN1 P39748 1/20 0.38
PDE4A P27815 7/20 0.35
PDE4B Q07343 6/20 0.35
PDE4C Q08493 6/20 0.35
PDE4D Q08499 6/20 0.35
PDE10A Q9Y233 1/20 0.32
LDHA P00338 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSPO P30536 1/20 0.32
PDE1A P54750 1/20 0.31
PDE1B Q01064 1/20 0.31
NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30327105 0.91 ALDH1A1 (0.45) ALDH1A1TSHRCYP2C19FEN1PDE4A
SCHEMBL30327323 0.90 ALDH1A1 (0.44) ALDH1A1TSHRCYP2C19FEN1PDE4A
SCHEMBL28975379 0.90 ALDH1A1 (0.44) ALDH1A1TSHRCYP2C19FEN1PDE4A
SCHEMBL17124144 0.89 MAT2A (0.33) ALDH1A1TSHRCYP2C19KDM4ENPY5R
SCHEMBL30327357 0.87 ALDH1A1 (0.43) ALDH1A1TSHRCYP2C19FEN1PDE4A
SCHEMBL16557341 0.87 KDM4E (0.44) ALDH1A1TSHRCYP2C19KDM4EATM
SCHEMBL17124145 0.87 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19KDM4EL3MBTL1
SCHEMBL28975373 0.86 ALDH1A1 (0.42) ALDH1A1TSHRCYP2C19FEN1PDE4A
SCHEMBL30327409 0.86 ALDH1A1 (0.42) ALDH1A1TSHRCYP2C19FEN1PDE4A
SCHEMBL30327234 0.86 ALDH1A1 (0.42) ALDH1A1TSHRCYP2C19FEN1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290814-B2 Organic light-emitting diode LG DISPLAY CO., LTD. (KR) 2019-05-14 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed