SCHEMBL17124145

SCHEMBL17124145

c1ccc(-c2ccc(N(c3ccc(-c4ccc5c(c4)c4cccnc4n5-c4ccccn4)cc3)c3ccccn3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.33
MEN1 O00255 3/20 0.33
LMNA P02545 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 1/20 0.33
UHRF1 Q96T88 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSPO P30536 1/20 0.33
PLAUR Q03405 1/20 0.33
NOX4 Q9NPH5 1/20 0.32
NOX1 Q9Y5S8 1/20 0.32
MAT2A P31153 1/20 0.32
PTGER4 P35408 1/20 0.32
FFAR4 Q5NUL3 3/20 0.32
HPGD P15428 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17124144 0.96 MAT2A (0.33) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL17124132 0.93 NPC1 (0.32) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL17124110 0.92 ALDH1A1 (0.35) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL17124142 0.91 ALDH1A1 (0.36) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL17124055 0.89 ALDH1A1 (0.40) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL17124137 0.87 ALDH1A1 (0.39) ALDH1A1KDM4ETSHRCYP2C19TSPO
SCHEMBL17124125 0.86 MEN1 (0.33) ALDH1A1MEN1LMNAKMT2ATSHR
SCHEMBL17124061 0.86 ALDH1A1 (0.39) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL17124130 0.85
SCHEMBL17124056 0.85 ALDH1A1 (0.39) ALDH1A1MEN1LMNAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2927978-B1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO LTD (KR) 2020-03-18 EP disclosed
US-10290814-B2 Organic light-emitting diode LG DISPLAY CO., LTD. (KR) 2019-05-14 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed