Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291057 | 0.86 | PRKCA (0.47) | TSHRPRKCAHSD17B10MGAMGAA | |
| SCHEMBL17124712 | 0.81 | PRKCA (0.44) | TSHRPRKCAMMP1MMP2MMP3 | |
| SCHEMBL765893 | 0.78 | SLC22A6 (0.45) | TSHRPRKCASLC22A6MAPTCACNA2D1 | |
| SCHEMBL12268201 | 0.77 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL148546 | 0.77 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL286783 | 0.77 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL28704878 | 0.76 | SLC22A6 (0.43) | TSHRPRKCASLC22A6MAPTCACNA2D1 | |
| (R)-3-Hydroxybutanoate SCHEMBL29048487 | 0.76 | TSHR (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL28861626 | 0.76 | TSHR (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL4290966 | 0.75 | TSHR (0.44) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148524-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | IOWA STATE UNIV RESEACH FOUNDATION INC (US) | 2018-05-31 | — | — | US | disclosed |
| US-20170226243-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | UNIV IOWA STATE RES FOUND INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-9688794-B2 | Tackifier compounds and methods of using the same | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20150274861-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274861-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | ORC3, OR10J3, NR2C2 | TSHR 580/4885PRKCA 4872/4885HSD17B10 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.