Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15015930 | 1.00 | TSHR (0.40) | TSHRHCAR2TP53MMP1MMP2 | |
| SCHEMBL5728799 | 0.90 | TSHR (0.48) | TSHRHCAR2PDCD1CD274CA12 | |
| SCHEMBL5856841 | 0.85 | TSHR (0.48) | TSHRHCAR2PDCD1CD274CA12 | |
| SCHEMBL27638248 | 0.82 | TSHR (0.46) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL11764621 | 0.82 | TSHR (0.46) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL20204485 | 0.79 | TSHR (0.39) | TSHRHCAR2SMN1; SMN2 | |
| SCHEMBL16438180 | 0.79 | TP53 (0.50) | TSHRTP53SLC7A5 | |
| SCHEMBL659817 | 0.79 | TP53 (0.50) | TSHRTP53SLC7A5 | |
| SCHEMBL18489590 | 0.79 | MAPT (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL17124702 | 0.78 | SMN1; SMN2 (0.50) | TP53SLC7A5CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111185241-B | Metal catalyst and preparation method and application thereof | 邯郸学院 | 2022-08-02 | — | — | CN | disclosed |
| US-20180148524-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | IOWA STATE UNIV RESEACH FOUNDATION INC (US) | 2018-05-31 | — | — | US | disclosed |
| US-9920145-B2 | Tackifier compounds and methods of using the same | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170226243-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | UNIV IOWA STATE RES FOUND INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-9688794-B2 | Tackifier compounds and methods of using the same | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20150274861-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274861-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | ORC3, OR10J3, NR2C2 | TSHR 580/4885HCAR2 288/4885TP53 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.