SCHEMBL5728799

SCHEMBL5728799

CC(C)OC(=O)C(C(C)C)C(C(=O)OC(C)C)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
HCAR2 Q8TDS4 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
CA12 O43570 7/20 0.34
CA1 P00915 7/20 0.34
CA2 P00918 7/20 0.34
CA9 Q16790 7/20 0.34
CA7 P43166 4/20 0.34
CA14 Q9ULX7 4/20 0.34
LMNA P02545 3/20 0.33
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADRA1A P35348 1/20 0.32
PDE4D Q08499 1/20 0.32
KDM4E B2RXH2 2/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5856841 0.94 TSHR (0.48) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL11764621 0.92 TSHR (0.46) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL17124707 0.90 TSHR (0.40) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL15015930 0.90 TSHR (0.40) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL20204485 0.88 TSHR (0.39) TSHRHCAR2SMN1; SMN2
SCHEMBL5077477 0.77 TSHR (0.48) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL9999821 0.77 TSHR (0.48) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL682227 0.77 TSHR (0.48) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL6063743 0.77 TSHR (0.48) TSHRHCAR2SMN1; SMN2CA12CA1
SCHEMBL295903 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478863-B Catalyst component for olefin polymerization and preparation method thereof, catalyst and application thereof, and polyolefin and preparation method thereof 中国石油化工股份有限公司 2023-09-08 CN claimed
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN claimed
CN-114773506-A Catalyst for in-situ nucleation of polypropylene and preparation method and application thereof 山东京博石油化工有限公司 2022-07-22 CN claimed
CN-114478863-A Catalyst component for olefin polymerization, preparation method thereof, catalyst and application thereof, polyolefin and preparation method thereof 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-119176891-A Ziegler-Natta catalyst for olefin polymerization and preparation method thereof 中国科学院大连化学物理研究所 2024-12-24 CN disclosed
CN-119161511-A Solid catalyst for olefin polymerization 中国科学院大连化学物理研究所 2024-12-20 CN disclosed
CN-118829663-A Catalyst for olefin polymerization, process for producing olefin polymer, and propylene homopolymer 东邦钛株式会社 2024-10-22 CN disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
CN-115515988-B Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2024-06-21 CN disclosed
CN-114478863-B Catalyst component for olefin polymerization and preparation method thereof, catalyst and application thereof, and polyolefin and preparation method thereof 中国石油化工股份有限公司 2023-09-08 CN disclosed
CN-116589617-A Polyolefin catalyst containing nucleating agent and preparation method and application thereof 山东京博石油化工有限公司 2023-08-15 CN disclosed
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN disclosed
CN-115515988-A Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2022-12-23 CN disclosed
CN-114773506-A Catalyst for in-situ nucleation of polypropylene and preparation method and application thereof 山东京博石油化工有限公司 2022-07-22 CN disclosed
CN-114478863-A Catalyst component for olefin polymerization, preparation method thereof, catalyst and application thereof, polyolefin and preparation method thereof 中国石油化工股份有限公司 2022-05-13 CN disclosed
EP-1088009-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-08-02 EP disclosed
US-20050032633-A1 Propylene polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-02-10 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed