Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728799 | 0.88 | TSHR (0.48) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL5856841 | 0.83 | TSHR (0.48) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL11764621 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL17124707 | 0.79 | TSHR (0.40) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL15015930 | 0.79 | TSHR (0.40) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL882109 | 0.69 | TSHR (0.43) | TSHRHCAR2 | |
| SCHEMBL682227 | 0.67 | TSHR (0.48) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL9999821 | 0.67 | TSHR (0.48) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL5077477 | 0.67 | TSHR (0.48) | TSHRSMN1; SMN2HCAR2 | |
| SCHEMBL21811751 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280241-B2 | Tackifier compounds and methods of using the same | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-05-07 | — | — | US | disclosed |
| US-20180148524-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | IOWA STATE UNIV RESEACH FOUNDATION INC (US) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280241-B2 | Tackifier compounds and methods of using the same | ORC3, OR10J3, NR2C2 | TSHR 580/4885SMN1; SMN2 2964/4885HCAR2 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.