SCHEMBL17126977

SCHEMBL17126977

CCCCSC(C(=O)c1ccc(Oc2ccc(OCC)cc2)cc1)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP10 Q53GL7 1/20 0.44
▸ SLC2A1 P11166 1/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ PAX8 Q06710 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ TAS1R3 Q7RTX0 1/20 0.40
▸ TAS1R1 Q7RTX1 1/20 0.40
▸ LTA4H P09960 2/20 0.40
▸ PLK1 P53350 1/20 0.40
▸ NPSR1 Q6W5P4 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17127025 0.96 PARP10 (0.43) PARP10SLC2A1NPC1RAB9ALMNA
SCHEMBL17127026 0.89 HDAC3 (0.47) PARP10SLC2A1NPC1RAB9ALTA4H
SCHEMBL17126974 0.89 PARP10 (0.46) PARP10SLC2A1LMNAHTTSMN1; SMN2
SCHEMBL17127365 0.87 PARP10 (0.45) PARP10NPC1RAB9ALMNAHTT
SCHEMBL17127019 0.87 LMNA (0.41) PARP10SLC2A1NPC1RAB9ALMNA
SCHEMBL17127027 0.85 PARP10 (0.44) PARP10SLC2A1LMNAHTTSMN1; SMN2
SCHEMBL17127336 0.85 HDAC3 (0.46) PARP10LTA4HTP53TSHR
SCHEMBL17126978 0.84 CETP (0.40) SLC2A1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL17777239 0.83 SLC2A1 (0.48) SLC2A1SMN1; SMN2L3MBTL1ALDH1A1HPGD
SCHEMBL17127028 0.81 CETP (0.42) NPC1RAB9ALMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE TERB1, ACTR5, ADPRS PARP10 611/4885SLC2A1 4878/4885NPC1 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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