SCHEMBL17127337

SCHEMBL17127337

CCOCCSC(C(=O)c1ccc2c(c1)Oc1ccccc1O2)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ HPGD P15428 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.34
▸ CTNNB1 P35222 1/20 0.33
▸ ALOX5 P09917 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.31
▸ BLM P54132 1/20 0.31
▸ PPARG P37231 1/20 0.31
▸ ATM Q13315 1/20 0.30
▸ TRPA1 O75762 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17127342 0.88 MEN1 (0.32) KMT2AMEN1NPC1HPGDSMN1; SMN2
SCHEMBL17126982 0.88 ACSL1 (0.39) KMT2AMEN1NPC1HPGDSMN1; SMN2
SCHEMBL17126979 0.82 PRSS1 (0.40) KMT2AMEN1NPC1SMN1; SMN2RAB9A
SCHEMBL17127030 0.82 MCHR1 (0.39) NPC1HPGDRAB9AKDM4EALDH1A1
SCHEMBL17127029 0.79 NPC1 (0.49) KMT2AMEN1NPC1HPGDRAB9A
SCHEMBL17126976 0.78 PPARA (0.40) NPC1HPGDSMN1; SMN2RAB9AALDH1A1
SCHEMBL15935680 0.76 SMN1; SMN2 (0.46) KMT2AMEN1HPGDSMN1; SMN2HTT
SCHEMBL17127022 0.76 PTGS2 (0.38) KMT2AMEN1NPC1SMN1; SMN2RAB9A
SCHEMBL17126859 0.75 PLA2G1B (0.33) KMT2AMEN1HTTALDH1A1
SCHEMBL17777239 0.74 SLC2A1 (0.48) KMT2AMEN1HPGDSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE TERB1, ACTR5, ADPRS KMT2A 1775/4885MEN1 3840/4885NPC1 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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