SCHEMBL1712834

SCHEMBL1712834

Cc1cc(Nc2ccccc2)c(Nc2ccccc2)cc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.55
HSD17B10 Q99714 3/20 0.52
HPGD P15428 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52
MAPT P10636 7/20 0.50
ALDH1A1 P00352 6/20 0.50
TDP1 Q9NUW8 6/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALOX15 P16050 4/20 0.50
KDM4E B2RXH2 3/20 0.50
LMNA P02545 3/20 0.50
GLA P06280 2/20 0.50
MAPK1 P28482 2/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
EGFR P00533 2/20 0.50
SRC P12931 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
RGS12 O14924 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21480028 0.91 GAA (0.56) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL12345612 0.90 GAA (0.60) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL1713297 0.87 PTGER4 (0.53) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL27906204 0.85 GAA (0.47) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL5080930 0.84 HSD17B10 (0.65) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL15131708 0.83 GAA (0.58) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL2244770 0.80 RAPGEF4 (0.58) GAAHPGDMAPTALDH1A1TDP1
SCHEMBL304152 0.80 MAPT (0.56) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL22045336 0.79 GAA (0.50) GAAHSD17B10HPGDNPSR1MAPT
SCHEMBL10816038 0.79 MAPT (0.54) GAAHSD17B10HPGDNPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9882148-B2 Organic compound, field element, organic light-emitting element, display apparatus, image information-processing apparatus, lighting apparatus, image-forming apparatus, and exposure apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-30 US disclosed
US-9882148-B2 Organic compound, field element, organic light-emitting element, display apparatus, image information-processing apparatus, lighting apparatus, image-forming apparatus, and exposure apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-30 US disclosed
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
WO-2015198579-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-30 WO disclosed
US-8865321-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-21 US disclosed
US-8865321-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-21 US disclosed
US-8865321-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-21 US disclosed
EP-2344607-B1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-04-10 EP disclosed
EP-2344607-B1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-04-10 EP disclosed
US-20110201778-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2011-08-18 US disclosed
US-20110201778-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2011-08-18 US disclosed
US-20110201778-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2011-08-18 US disclosed
EP-2344607-A1 ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2011-07-20 EP disclosed
WO-2010054730-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-05-20 WO disclosed
WO-2010054730-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS SCO2, OGFOD1, OXER1 GAA 3879/4885HSD17B10 3546/4885HPGD 1843/4885
US-20110201778-A1 Organic Electroluminescent Devices L1CAM, PIEZO1, OR10J3 GAA 1918/4885HSD17B10 2023/4885HPGD 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.