Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.63 |
| ▸ | LIPE | Q05469 | 1/20 | 0.54 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340329 | 0.83 | ADAMTS5 (0.61) | ADAMTS5CCR1 | |
| SCHEMBL23873216 | 0.79 | LIPE (0.47) | EPHX2LIPECCR1P2RY14 | |
| SCHEMBL2636716 | 0.79 | LIPE (0.52) | LIPEP2RY14 | |
| SCHEMBL31487378 | 0.79 | RBP4 (0.63) | EPHX2 | |
| SCHEMBL8220312 | 0.78 | LIPE (0.50) | EPHX2LIPEP2RY14 | |
| SCHEMBL17130354 | 0.78 | EPHX2 (0.66) | EPHX2ADAMTS5 | |
| SCHEMBL23873320 | 0.78 | CHRM2 (0.44) | EPHX2LIPECCR1P2RY14 | |
| SCHEMBL5535882 | 0.77 | LIPE (0.51) | LIPECCR1P2RY14 | |
| SCHEMBL2730089 | 0.77 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL15155469 | 0.77 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015148954-A1 | POTENT SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EICOSIS, LLC (US) | 2015-10-01 | — | — | WO | disclosed |