SCHEMBL1713040

SCHEMBL1713040

O=C(OC#Cc1ccccc1)c1ccc(C(=O)OC#Cc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
F2 P00734 1/20 0.46
VCP P55072 1/20 0.46
APP P05067 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 2/20 0.43
FFAR1 O14842 2/20 0.43
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GRM5 P41594 2/20 0.41
MEN1 O00255 1/20 0.41
HSP90AA1 P07900 1/20 0.41
OPRK1 P41145 1/20 0.41
KMT2A Q03164 1/20 0.41
RAB9A P51151 1/20 0.41
PTPN11 Q06124 1/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PAM P19021 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2256472 0.96 LMNA (0.52) LMNAF2VCPAPPTDP1
SCHEMBL2745851 0.94 TSHR (0.46) LMNAF2VCPTDP1TSHR
SCHEMBL15611389 0.89 TSHR (0.50) LMNAF2TDP1TSHRPTPN11
SCHEMBL1713010 0.86 TDP1 (0.45) LMNAF2VCPAPPTDP1
SCHEMBL38695 0.83 NPC1 (0.47) LMNAAPPTDP1TSHRFFAR1
SCHEMBL28358478 0.79 ALDH1A1 (0.54) LMNAAPPTDP1TSHRMAPT
SCHEMBL23880583 0.79 APP (0.44) LMNAF2VCPAPPFFAR1
SCHEMBL9364505 0.79 NPSR1 (0.46) LMNAVCPAPPTSHRFFAR1
SCHEMBL2746516 0.79 ALDH1A1 (0.52) APPFFAR1MAPTALDH1A1RAB9A
SCHEMBL3137431 0.79 ALDH1A1 (0.55) LMNAVCPAPPTSHRFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344568-B1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2017-12-20 EP claimed
US-8492507-B2 Acetylenic polyamide NEXAM CHEMICAL AB (SE) 2013-07-23 US claimed
US-20110190469-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2011-08-04 US claimed
EP-2344568-A1 ACETYLENIC POLYAMIDE Nexam Chemical AB (SE) 2011-07-20 EP claimed
WO-2010036170-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2010-04-01 WO claimed
WO-2010030216-A1 ACETYLENIC POLY(ALKYLENE PHTHALATE) NEXAM CHEMICAL AB (SE) 2010-03-18 WO claimed
CN-115197565-B Semi-crystalline polyamide composition based on short diamines with high glass transition temperature, process for its production and use thereof 阿科玛法国公司 2024-10-11 CN disclosed
CN-115197565-A Semi-crystalline polyamide composition based on short diamines with high glass transition temperature, method for the production thereof and use thereof 阿科玛法国公司 2022-10-18 CN disclosed
CN-110446740-B Semi-crystalline polyamide compositions based on short diamines with high glass transition temperature, method for the production thereof and use thereof 阿科玛法国公司 2022-07-12 CN disclosed
CN-110431169-B Semi-crystalline polyamide composition having a high glass transition temperature and a high melting temperature, method for preparing same and use thereof 阿科玛法国公司 2022-05-17 CN disclosed
EP-2344568-B1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2017-12-20 EP disclosed
US-8492507-B2 Acetylenic polyamide NEXAM CHEMICAL AB (SE) 2013-07-23 US disclosed
CN-102174183-B High-temperature self-crosslinking flame-retardant anti-dripping copolyester and preparation method thereof UNIV SICHUAN 2012-07-25 CN disclosed
US-20110190469-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2011-08-04 US disclosed
EP-2344568-A1 ACETYLENIC POLYAMIDE Nexam Chemical AB (SE) 2011-07-20 EP disclosed
WO-2010036170-A1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2010-04-01 WO disclosed
WO-2010036175-A1 MOULDED ARTICLE OBTAINED FROM ACETYLENIC POLYAMIDE NEXAM CHEMICALS (SE) 2010-04-01 WO disclosed
WO-2010030216-A1 ACETYLENIC POLY(ALKYLENE PHTHALATE) NEXAM CHEMICAL AB (SE) 2010-03-18 WO disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed