Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490671 | 0.77 | PDE4D (0.36) | — | |
| SCHEMBL13490644 | 0.75 | CCR1 (0.42) | GRM5 | |
| SCHEMBL13592737 | 0.75 | CHRM2 (0.31) | — | |
| SCHEMBL169422 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL13592761 | 0.68 | CHRM1 (0.40) | — | |
| SCHEMBL13592661 | 0.68 | TP53 (0.36) | HRH3KMT2A | |
| SCHEMBL171149 | 0.64 | SIGMAR1 (0.50) | KMT2A | |
| SCHEMBL20799456 | 0.62 | HSD17B1 (0.56) | GRM5APPFFAR1 | |
| SCHEMBL12854780 | 0.62 | APP (0.52) | APPFFAR1KMT2A | |
| SCHEMBL4569961 | 0.62 | NPC1 (0.57) | GRM5APPFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |