Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490644 | 0.77 | CCR1 (0.42) | CHRM2CHRM3 | |
| SCHEMBL169361 | 0.75 | CDK13 (0.34) | — | |
| SCHEMBL13592737 | 0.75 | CHRM2 (0.31) | CHRM2CHRM3 | |
| SCHEMBL171305 | 0.70 | HRH3 (0.37) | — | |
| SCHEMBL13490404 | 0.65 | CHRM1 (0.32) | CHRM2CHRM3 | |
| SCHEMBL13490678 | 0.60 | CHRM2 (0.37) | CHRM2CHRM3 | |
| SCHEMBL11265059 | 0.58 | KDM4E (0.51) | KDM4EALDH1A1LMNAMAPTPKM | |
| SCHEMBL25813010 | 0.58 | CA12 (0.42) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL25813014 | 0.58 | HCAR3 (0.40) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL13397872 | 0.57 | CA12 (0.61) | KDM4ENPC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |