SCHEMBL17130664

SCHEMBL17130664

CS(=O)(=O)On1c(=O)c2ccc(F)cc2c2cc(F)ccc2c1=O

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ACHE P22303 1/20 0.36
MPI P34949 4/20 0.36
PMM2 O15305 3/20 0.36
MIF P14174 2/20 0.36
PHOSPHO1 Q8TCT1 2/20 0.36
APOBEC3G Q9HC16 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
FEN1 P39748 2/20 0.35
ATM Q13315 1/20 0.35
G6PD P11413 1/20 0.35
KAT2B Q92831 1/20 0.35
SYK P43405 1/20 0.34
MPO P05164 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17130702 0.94 ATM (0.41) BRD4MPIPMM2PHOSPHO1APOBEC3G
SCHEMBL17130662 0.93 BRD4 (0.40) BRD4MPIPMM2MIFPHOSPHO1
SCHEMBL17130670 0.80 TXNRD1 (0.41) MPIPMM2MIFPHOSPHO1NPC1
SCHEMBL17130661 0.80 CA1 (0.35) BRD4CA1CA2ACHEMPI
SCHEMBL3827616 0.79 ALDH1A1 (0.36) CA1CA2
SCHEMBL17130660 0.79 CA1 (0.34) BRD4CA1CA2ACHEMPI
SCHEMBL17130665 0.79 VDR (0.46) BRD4CA1CA2ACHEMPI
SCHEMBL17130613 0.78 MAPK1 (0.41) CA1CA2KDM4E
SCHEMBL17130701 0.75 MPI (0.38) BRD4CA1CA2ACHEMPI
SCHEMBL17130705 0.74 VDR (0.48) BRD4KAT2BMPOKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015146053-A1 IMIDE SULFONATE COMPOUND, PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY サンアプロ株式会社 2015-10-01 WO disclosed