Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407425 | 0.93 | ALDH1A1 (0.50) | ALDH1A1CA12CA9MCOLN3NR3C2 | |
| SCHEMBL25137428 | 0.82 | CA12 (0.55) | CA12CA9MCOLN3NR3C2HTT | |
| SCHEMBL10262610 | 0.81 | CA12 (0.50) | ALDH1A1CA12CA9MCOLN3NR3C2 | |
| SCHEMBL11551098 | 0.80 | CA12 (0.53) | CA12CA9MCOLN3NR3C2HTT | |
| Lithium SCHEMBL31041149 | 0.80 | CA12 (0.53) | CA12CA9MCOLN3NR3C2HTT | |
| SCHEMBL841253 | 0.78 | CA12 (0.52) | CA12CA9MCOLN3NR3C2HTT | |
| SCHEMBL17227595 | 0.78 | CA12 (0.52) | CA12CA9MCOLN3NR3C2HTT | |
| SCHEMBL5228279 | 0.78 | CA12 (0.52) | ALDH1A1CA12CA9MCOLN3NR3C2 | |
| SCHEMBL21034450 | 0.78 | CA12 (0.52) | ALDH1A1CA12CA9MCOLN3NR3C2 | |
| SCHEMBL3043906 | 0.78 | CA12 (0.52) | CA12CA9MCOLN3NR3C2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140005163-A1 | 1H-IMIDAZO[4,5-C]QUINOLINONE DERIVATIVES | NOVARTIS AG (CH) | 2014-01-02 | — | — | US | claimed |
| EP-2438063-A1 | 1H-IMIDAZO[4,5-C]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-04-11 | — | — | EP | claimed |
| CN-101287805-B | Marine antifouling coating compositions | NOVUS INT INC | 2011-11-02 | — | — | CN | claimed |
| US-20100317657-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES | NOVARTIS AG | 2010-12-16 | — | — | US | claimed |
| WO-2010139747-A1 | 1H-IMIDAZO[4, 5-c]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2010-12-09 | — | — | WO | claimed |
| US-20100311714-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE COMPOUNDS | NOVARTIS AG (CH) | 2010-12-09 | — | — | US | claimed |
| CN-101287805-A | Marine antifouling coating compositions | NOVUS INT INC (US) | 2008-10-15 | — | — | CN | claimed |
| EP-1910477-A1 | USE OF A COMBINATION OF SUBSTANCES TO PREVENT BIOFOULING ORGANISMS | I-Tech AB (SE) | 2008-04-16 | — | — | EP | claimed |
| WO-2007015676-A1 | USE OF A COMBINATION OF SUBSTANCES TO PREVENT BIOFOULING ORGANISMS | I-TECH AB (SE) | 2007-02-08 | — | — | WO | claimed |
| CN-1717176-A | Fungicidal compositions | ISAGRO SPA (IT) | 2006-01-04 | — | — | CN | claimed |
| CN-1107449-C | Liquid preservative for fruit and vegetable storage and preparation method thereof | STATE AGRICULTURAL PRODUCT PRE (CN) | 2003-05-07 | — | — | CN | claimed |
| CN-1334012-A | Liquid preservative for fruit and vegetable storage and preparation method thereof | STATE AGRICULTURAL PRODUCT PRE (CN) | 2002-02-06 | — | — | CN | claimed |
| CN-1314083-A | Sterilizing agent composition | SHENYANG CHEMIAL RES INST (CN) | 2001-09-26 | — | — | CN | claimed |
| CN-1029814-C | bactericidal composition | SHELL INT RESEARCH (NL) | 1995-09-27 | — | — | CN | claimed |
| EP-0549668-A1 | ANTI-HYPERTENSIVE TETRALINS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-07 | — | — | EP | claimed |
| WO-1992005143-A1 | ANTI-HYPERTENSIVE TETRALINS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | claimed |
| CN-1030003-A | bactericidal composition | SHELL AGRAR GMBH & CO KG (DE) | 1989-01-04 | — | — | CN | claimed |
| EP-3838903-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE AS JANUS KINASE INHIBITOR | INCYTE HOLDINGS CORP (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-87102872-A | Stable pesticidal preparations | — | 1987-10-28 | — | — | CN | disclosed |
| CN-86108526-A | Bactericide | — | 1987-07-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311714-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE COMPOUNDS | PRKCA, ABL1, MYLK2 | ALDH1A1 2472/4885CA12 4812/4885CA9 4676/4885 |
| US-20100317657-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES | PRKCA, CSNK1A1, ABL1 | ALDH1A1 2405/4885CA12 4835/4885CA9 4728/4885 |
| US-20140005163-A1 | 1H-IMIDAZO[4,5-C]QUINOLINONE DERIVATIVES | PRKCA, CSNK1A1, ABL1 | ALDH1A1 2405/4885CA12 4835/4885CA9 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.