SCHEMBL841253

SCHEMBL841253

CN(c1ccccc1)S(N)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.52
CA9 Q16790 3/20 0.52
KIF11 P52732 1/20 0.52
MCOLN3 Q8TDD5 1/20 0.46
MEN1 O00255 2/20 0.44
HTT P42858 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ENPP1 P22413 1/20 0.44
CA2 P00918 3/20 0.44
CA1 P00915 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
PLA2G7 Q13093 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25137428 0.80 CA12 (0.55) CA12CA9MCOLN3MEN1HTT
SCHEMBL171307 0.78 ALDH1A1 (0.54) CA12CA9MCOLN3MEN1HTT
Lithium SCHEMBL31041149 0.78 CA12 (0.53) CA12CA9MCOLN3MEN1HTT
SCHEMBL11551098 0.78 CA12 (0.53) CA12CA9MCOLN3MEN1HTT
SCHEMBL1185553 0.77 KIF11 (0.53) CA12CA9KIF11MCOLN3KDM4E
SCHEMBL1646284 0.77 KIF11 (0.58) CA12CA9KIF11MCOLN3MEN1
SCHEMBL5388755 0.77 KIF11 (0.49) CA12CA9KIF11MCOLN3MEN1
SCHEMBL22638692 0.77 CA2 (0.52) CA12CA9KIF11MEN1KMT2A
SCHEMBL21034450 0.76 CA12 (0.52) CA12CA9MCOLN3MEN1HTT
SCHEMBL5228279 0.76 CA12 (0.52) CA12CA9MCOLN3MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087687-A Method for direct carbon-hydrogen alkynylation of thioamide-oriented aromatic hydrocarbon 宁夏大学 2021-07-09 CN claimed
JP-2597176-B2 1997-04-02 JP claimed
WO-1988005630-A1 FUNGICIDAL COMPOSITIONS SHELL AGRAR GMBH & CO. KG (DE) 1988-08-11 WO claimed
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES MONDEGO BIO, LDA. (PT) 2024-08-08 US disclosed
EP-4351558-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES Ness Therapeutics, Inc. (US) 2024-04-17 EP disclosed
WO-2022261145-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES NESS THERAPEUTICS, INC. (US) 2022-12-15 WO disclosed
US-20170015649-A1 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2017-01-19 US disclosed
US-9365543-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE 2016-06-14 US disclosed
US-20150353523-A1 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2015-12-10 US disclosed
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
US-9056853-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2015-06-16 US disclosed
US-20020169072-A1 Olefin polymerization catalyst and process for produing Olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2002-11-14 US disclosed
EP-1238989-A2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst Mitsui Chemicals, Inc. (JP) 2002-09-11 EP disclosed
EP-0849630-B1 Process for producing color filter FUJI PHOTO FILM CO LTD (JP) 2001-11-21 EP disclosed
EP-0849630-A2 Process for producing color filter FUJI PHOTO FILM CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0127162-B1 COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-11-15 EP disclosed
US-4842985-A COUPLER HAVING DYE MOIETY WITH SHIFTED MAXIMUM ABSORPTION WAVELENGTH, HUE-FIXING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-06-27 US disclosed
US-4585728-A 2-EQUIVALENT MAGENTA COUPLER AND AMINE FUJI PHOTO FILM CO., LTD. (JP) 1986-04-29 US disclosed
US-4555479-A CONTAINING 5-PYRAZOLONE TYPE MAGENTA COUPLERS AND NITROGEN COMPOUND-PREVENTION STAINING FUJI PHOTO FILM CO., LTD. (JP) 1985-11-26 US disclosed
EP-0127162-A2 Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES PPM1A, TH, PPM1G CA12 3236/4885CA9 1552/4885KIF11 3848/4885
US-20170015649-A1 N-Thio-anthranilamid compounds and their use as pesticides NAT1, AAAS, ACHE CA12 1964/4885CA9 1180/4885KIF11 4308/4885
US-20150353523-A1 N-Thio-anthranilamid compounds and their use as pesticides NAT1, AAAS, ACHE CA12 1964/4885CA9 1180/4885KIF11 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.