Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669108 | 0.82 | HTR1A (0.44) | MEN1KMT2AGRM5NOTUMGAA | |
| SCHEMBL799132 | 0.78 | MEN1 (0.38) | MEN1KMT2AGRM5CYP11B1CYP11B2 | |
| SCHEMBL21603224 | 0.74 | GRM5 (0.45) | MEN1KMT2AHPGDHTTHSD17B10 | |
| SCHEMBL568921 | 0.72 | PTGS1 (0.39) | MEN1KMT2AHPGDHTTHSD17B10 | |
| SCHEMBL10314871 | 0.70 | GRM5 (0.53) | GRM5CYP11B2 | |
| SCHEMBL19699124 | 0.70 | HTR1A (0.47) | GRM5 | |
| SCHEMBL31743068 | 0.70 | GRM5 (0.56) | MEN1KMT2AHTTGRM5CYP11B1 | |
| SCHEMBL10271348 | 0.69 | MAOA (0.37) | MEN1KMT2AHPGDHTTHSD17B10 | |
| SCHEMBL25256410 | 0.69 | MEN1 (0.41) | MEN1KMT2AHPGDHTTLMNA | |
| SCHEMBL31587247 | 0.69 | HTR1A (0.43) | MEN1KMT2AGRM5NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015146928-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2015-10-01 | — | — | WO | disclosed |