Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.47 |
| ▸ | HTR2A | P28223 | 13/20 | 0.47 |
| ▸ | DRD2 | P14416 | 10/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12573365 | 0.82 | ADAM17 (0.48) | HTR1AHTR2ADRD2CHRM2CHRM1 | |
| SCHEMBL29431445 | 0.82 | ADAM17 (0.48) | HTR1AHTR2ADRD2CHRM2CHRM1 | |
| SCHEMBL31484091 | 0.80 | DRD2 (0.39) | HTR1AHTR2ADRD2CHRM2CHRM1 | |
| SCHEMBL25596768 | 0.79 | HTR1A (0.45) | HTR1AHTR2ADRD2CHRM2CHRM1 | |
| SCHEMBL803066 | 0.79 | HTR1A (0.40) | HTR1AHTR2ADRD2CHRM2CHRM1 | |
| SCHEMBL3399553 | 0.79 | HTR1A (0.48) | HTR1AHTR2ADRD2ADAM17MTNR1A | |
| SCHEMBL11947839 | 0.75 | HTR1A (0.46) | HTR1AHTR2ADRD2ADAM17 | |
| SCHEMBL256377 | 0.74 | MTNR1A (0.50) | HTR1AHTR2ADRD2CHRM2CHRM1 | |
| SCHEMBL27252004 | 0.74 | HTR1A (0.48) | HTR1AHTR2ADRD2CHRM2CHRM1 | |
| SCHEMBL17881248 | 0.73 | CRBN (0.40) | HTR1AHTR2ADRD2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059845-A1 | SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2017214359-A1 | NOVEL CLOSTRIDIUM DIFFICILE TOXIN INHIBITORS | VENENUM BIODESIGN LLC (US) | 2017-12-14 | — | — | WO | disclosed |