SCHEMBL17133802

SCHEMBL17133802

Clc1cc2c3ccccc3n3c4ccccc4c(c1)c23

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.46
▸ MAPT P10636 2/20 0.46
▸ POLB P06746 2/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ GPR3 P46089 1/20 0.39
▸ CYP1A2 P05177 2/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ CYP19A1 P11511 1/20 0.38
▸ L3MBTL1 Q9Y468 3/20 0.37
▸ TSHR P16473 1/20 0.37
▸ ALOX12 P18054 1/20 0.37
▸ ATM Q13315 1/20 0.37
▸ ALKBH5 Q6P6C2 1/20 0.34
▸ FTO Q9C0B1 1/20 0.34
▸ BCHE P06276 1/20 0.34
▸ ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31658920 0.88 KDM4E (0.41) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL25414376 0.86 ALDH1A1 (0.41) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL19387982 0.84 MAPT (0.49) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL10153493 0.82 GPR3 (0.42) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL23288194 0.81 KDM4E (0.38) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL17133804 0.80 MAPT (0.49) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL17033347 0.80 KDM4E (0.41) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL29783091 0.80 MAPT (0.49) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL10015046 0.80 GPR3 (0.41) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL25982257 0.80 MDM2 (0.41) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480125-A Organic electroluminescent material and device 环球展览公司 2021-03-12 — — CN disclosed
CN-104974166-B Organic electroluminescent material and device 环球展览公司 2020-12-15 — — CN disclosed
WO-2020226295-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-11-12 — — WO disclosed
US-10686143-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-16 — — US disclosed
US-10177316-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-01-08 — — US disclosed
US-9929353-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-27 — — US disclosed
EP-2927234-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2016-09-28 — — EP disclosed
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERAL DISPLAY CORPORATION (US) 2016-09-08 — — US disclosed
US-20160233435-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-11 — — US disclosed
US-20150287933-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-10-08 — — US disclosed
EP-2927234-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2015-10-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, JUND KDM4E 1944/4885MAPT 840/4885POLB 2258/4885
US-20160233435-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBP2 KDM4E 4338/4885MAPT 1539/4885POLB 1870/4885
US-10686143-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, JUND KDM4E 1944/4885MAPT 840/4885POLB 2258/4885
US-10177316-B2 Organic electroluminescent materials and devices OSBP, OSBPL3, OSBP2 KDM4E 4338/4885MAPT 1539/4885POLB 1870/4885
US-20150287933-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND KDM4E 2566/4885MAPT 1112/4885POLB 1149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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