Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL379263 | 0.97 | HSD17B10 (0.50) | HSD17B10ALDH1A1TDP1PKMKMT2A | |
| Fluorobenzene SCHEMBL1713478 | 0.86 | HSD17B10 (0.46) | HSD17B10ALDH1A1TDP1PKMKMT2A | |
| Fluorobenzene SCHEMBL974376 | 0.86 | TSHR (0.46) | HSD17B10ALDH1A1TDP1PKMKMT2A | |
| Fluorobenzene SCHEMBL3600102 | 0.82 | FAAH (0.46) | HSD17B10ALDH1A1TDP1PKMKMT2A | |
| SCHEMBL2008144 | 0.82 | PTGS2 (0.47) | HSD17B10ALDH1A1TDP1PKMKMT2A | |
| Fluorobenzene SCHEMBL7167290 | 0.82 | ALDH1A1 (0.76) | HSD17B10ALDH1A1TDP1PKMKMT2A | |
| SCHEMBL1603078 | 0.82 | CA1 (0.46) | ALDH1A1PKMKMT2ATSHRMEN1 | |
| Fluorobenzene SCHEMBL27779529 | 0.82 | — | — | |
| Fluorobenzene SCHEMBL28000137 | 0.80 | PTGS2 (0.48) | HSD17B10PKMKMT2AHTR6NFE2L2 | |
| Fluorobenzene SCHEMBL28144867 | 0.80 | TSHR (0.50) | ALDH1A1PKMKMT2AHTR6NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |