Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.58 |
| ▸ | MMP12 | P39900 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17136559 | 0.94 | MMP8 (0.56) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17136431 | 0.92 | MMP8 (0.51) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17136510 | 0.92 | MMP8 (0.55) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17136504 | 0.92 | MMP8 (0.57) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17136377 | 0.91 | MMP8 (0.56) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17136503 | 0.91 | HTR2C (0.52) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17136546 | 0.89 | TRPA1 (0.54) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17199918 | 0.89 | TRPA1 (0.64) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17136539 | 0.89 | MMP8 (0.51) | MMP8MMP12MMP13ALDH1A1FKBP1A | |
| SCHEMBL17136454 | 0.89 | TRPA1 (0.55) | MMP8MMP12MMP13ALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937335-A1 | HETEROCYCLIC AMIDE DERIVATIVE, AND MEDICINE CONTAINING SAME | Ajinomoto Co., Inc. (JP) | 2015-10-28 | — | — | EP | disclosed |
| US-20150284375-A1 | HETEROCYCLIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284375-A1 | HETEROCYCLIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | TRPA1, TRPV1, TRPV2 | MMP8 1141/4885MMP12 2543/4885MMP13 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.