Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562346 | 0.93 | FAAH (0.58) | FAAHCNR1CNR2LMNAGPR84 | |
| SCHEMBL29061012 | 0.93 | FAAH (0.58) | FAAHCNR1CNR2LMNAGPR84 | |
| SCHEMBL27296733 | 0.93 | FAAH (0.58) | FAAHCNR1CNR2LMNAGPR84 | |
| SCHEMBL28788315 | 0.93 | FAAH (0.58) | FAAHCNR1CNR2LMNAGPR84 | |
| SCHEMBL27311668 | 0.93 | FAAH (0.58) | FAAHCNR1CNR2LMNAGPR84 | |
| SCHEMBL29608607 | 0.93 | FAAH (0.58) | FAAHCNR1CNR2LMNAGPR84 | |
| SCHEMBL1713745 | 0.92 | FAAH (0.54) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL28863965 | 0.91 | LMNA (0.50) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL10450191 | 0.91 | LMNA (0.55) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL11230135 | 0.89 | LMNA (0.58) | FAAHCNR1CNR2LMNAAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901360-A | Novel lipid nanoparticles for delivery of nucleic acids | 库瑞瓦格股份公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-3233889-B1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | SHANGHAI MICURX PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| CN-107257803-B | Polymyxin antibacterial agents for the treatment of bacterial infections | 上海盟科药业股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-3233889-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. | 2016-06-30 | — | — | US | disclosed |
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. | 2016-06-30 | — | — | US | disclosed |
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-1765529-B1 | PROCESS FOR STIMULATING PRODUCTION OF HYDROGEN FROM PETROLEUM IN SUBTERRANEAN FORMATIONS | UNIV NEWCASTLE (GB) | 2011-07-20 | — | — | EP | disclosed |
| EP-1776198-B1 | PROCESS FOR STIMULATING PRODUCTION OF METHANE FROM PETROLEUM IN SUBTERRANEAN FORMATIONS | UNIV NEWCASTLE (GB) | 2011-07-20 | — | — | EP | disclosed |
| US-20100035309-A1 | ANALYSIS AND ENHANCEMENT OF METABOLIC PATHWAYS FOR METHANOGENESIS | LUCA TECHNOLOGIES, INC. (US) | 2010-02-11 | — | — | US | disclosed |
| US-20070298479-A1 | Process For Stimulating Production Of Hydrogen From Petroleum In Subterranean Formations | NORSK HYDRO ASA (NO) | 2007-12-27 | — | — | US | disclosed |
| US-7304032-B2 | CD-10 activated prodrug compounds | MEDAREX, INC. (US) | 2007-12-04 | — | — | US | disclosed |
| US-20070251146-A1 | Process for Stimulating Production of Methane From Petroleum in Subterranean Formations | THE UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2007-11-01 | — | — | US | disclosed |
| EP-1776198-A1 | PROCESS FOR STIMULATING PRODUCTION OF METHANE FROM PETROLEUM IN SUBTERRANEAN FORMATIONS | University of Newcastle upon Tyne (GB) | 2007-04-25 | — | — | EP | disclosed |
| EP-1765529-A1 | PROCESS FOR STIMULATING PRODUCTION OF HYDROGEN FROM PETROLEUM IN SUBTERRANEAN FORMATIONS | University of Newcastle upon Tyne (GB) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005115648-A1 | PROCESS FOR STIMULATING PRODUCTION OF HYDROGEN FROM PETROLEUM IN SUBTERRANEAN FORMATIONS | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2005-12-08 | — | — | WO | disclosed |
| WO-2005115649-A1 | PROCESS FOR STIMULATING PRODUCTION OF METHANE FROM PETROLEUM IN SUBTERRANEAN FORMATIONS | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | VIP, AQP1, PEF1 | FAAH 3284/4885CNR1 4198/4885CNR2 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.