Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6521168 | 0.71 | MAPT (0.44) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL1217478 | 0.68 | MAPT (0.43) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL11673614 | 0.63 | MAPT (0.56) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL198065 | 0.62 | MAPT (0.61) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL19974112 | 0.61 | KDM4E (0.39) | MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL14486673 | 0.60 | KDM4E (0.38) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL6518268 | 0.59 | ALDH1A1 (0.39) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL2605854 | 0.59 | KDM4E (0.52) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL12170102 | 0.57 | MAPT (0.50) | MAPTKDM4EHIF1AHSD17B10MEN1 | |
| SCHEMBL23055877 | 0.57 | MAPT (0.69) | MAPTKDM4EHIF1AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-10-08 | — | — | US | claimed |
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | DHPS, COASY, CDK18 | MAPT 3539/4885KDM4E 2053/4885HIF1A 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.