Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 7/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236167 | 0.82 | SMN1; SMN2 (0.69) | KDM4ESMN1; SMN2CYP3A4HSD17B10TP53 | |
| SCHEMBL17138145 | 0.82 | ADORA3 (0.51) | KDM4ECYP3A4ALDH1A1ATMGAA | |
| SCHEMBL17138137 | 0.80 | BCHE (0.58) | KDM4ESMN1; SMN2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL2072196 | 0.77 | KDM4E (0.89) | KDM4ESMN1; SMN2CYP3A4HSD17B10TP53 | |
| SCHEMBL17138215 | 0.76 | ADORA3 (0.60) | KDM4ECYP3A4HSD17B10ALDH1A1ATM | |
| SCHEMBL20519927 | 0.70 | L3MBTL1 (0.57) | SMN1; SMN2CYP3A4ALDH1A1ATMGAA | |
| SCHEMBL17138198 | 0.70 | GAA (0.45) | CYP3A4ATMGAAXBP1NPSR1 | |
| SCHEMBL14286960 | 0.69 | L3MBTL1 (0.53) | SMN1; SMN2ALDH1A1ATMGAAXBP1 | |
| SCHEMBL28282719 | 0.69 | L3MBTL1 (0.59) | SMN1; SMN2CYP3A4ALDH1A1ATMGAA | |
| SCHEMBL11940752 | 0.69 | ALDH2 (0.65) | KDM4ESMN1; SMN2CYP3A4HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | RNS CO.,LTD. (KR) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | HRH3, CBR3, H1-0 | KDM4E 494/4885SMN1; SMN2 1635/4885CYP3A4 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.