Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.58 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628125 | 0.82 | PTGDR2 (0.67) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL14340636 | 0.81 | MAPT (0.77) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL15415062 | 0.80 | TRPV4 (0.50) | TSHR | |
| SCHEMBL4628496 | 0.79 | MAPT (0.79) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL11113035 | 0.78 | MAPT (0.77) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL121636 | 0.78 | MAPT (1.00) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL15052213 | 0.77 | PTGER1 (0.39) | MAPTTSHR | |
| SCHEMBL12830790 | 0.77 | MAPT (0.74) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL1372961 | 0.77 | MAPT (0.97) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL11106300 | 0.77 | MAPT (0.74) | MAPTPTGDR2PTGDRTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | PAOX, PCCA, PAH | MAPT 1955/4885PTGDR2 236/4885PTGDR 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.