Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418940 | 0.87 | P2RX7 (0.61) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL1111138 | 0.87 | P2RX7 (0.61) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL29502563 | 0.85 | MAPT (0.50) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL22836314 | 0.85 | MAPT (0.50) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL16369847 | 0.85 | MAPT (0.50) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| Methyl Alcohol SCHEMBL17966403 | 0.85 | P2RX7 (0.59) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL17138421 | 0.84 | MAPT (0.47) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL17138402 | 0.83 | MAPT (0.46) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL2627807 | 0.81 | CYP1A2 (0.53) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL16834606 | 0.80 | MAPT (0.48) | MAPTP2RX7CYP1A2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284341-A1 | FLUOROALKYL-SUBSTITUTED DERIVATIVES OF PYRIDINE, PYRIMIDINE, AND PYRAZINE | CATYLIX INC (US) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284341-A1 | FLUOROALKYL-SUBSTITUTED DERIVATIVES OF PYRIDINE, PYRIMIDINE, AND PYRAZINE | PFAS, AFF2, AFF4 | MAPT 3445/4885P2RX7 160/4885CYP1A2 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.