SCHEMBL1713865

SCHEMBL1713865

c1ccc(SC(Sc2ccccc2)Sc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
MGLL Q99685 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPK1 P28482 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
SLC6A4 P31645 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
GAA P10253 2/20 0.36
KDM4E B2RXH2 2/20 0.36
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4594959 0.91 SMN1; SMN2 (0.43) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL343269 0.81 SMN1; SMN2 (0.45) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL1453001 0.81 SMN1; SMN2 (0.45) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL5173197 0.81 SMN1; SMN2 (0.45) SMN1; SMN2MAPTHPGDMGLLHSD17B10
Fluoride SCHEMBL1336886 0.79 MAOA (0.48) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL24012949 0.77 MAOA (0.41) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL3885342 0.77 MAOA (0.41) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL9427770 0.77 MAOA (0.41) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL7362590 0.77 MAOA (0.52) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL23331965 0.77 MAOA (0.52) SMN1; SMN2MAPTHPGDMGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109609973-B Preparation method and application of organic sulfide modified carbon nanotube loaded low-content palladium composite material 温州大学 2020-12-22 CN claimed
US-8987430-B2 Efficient and scalable process for the manufacture of fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2015-03-24 US claimed
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
CN-113993719-A Trisulfide compound 住友化学株式会社 2022-01-28 CN disclosed
US-20200409221-A1 LIQUID CRYSTAL SENSOR PLATYPUS TECHNOLOGIES, LLC 2020-12-31 US disclosed
CN-109609973-B Preparation method and application of organic sulfide modified carbon nanotube loaded low-content palladium composite material 温州大学 2020-12-22 CN disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
EP-2809678-B1 AN EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORP (US) 2017-03-22 EP disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
US-20160274084-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC 2016-09-22 US disclosed
US-9417245-B2 Porphyrinic compounds for use in flow cytometry NORTH CAROLINA STATE UNIVERSITY (US) 2016-08-16 US disclosed
WO-2004000887-A1 COMPOUNDS THAT BIND TO THE INTERFERON-GAMMA, PREPARATION METHOD THEREOF AND MEDICAMENTS CONTAINING SAME COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2003-12-31 WO disclosed
EP-0700291-B1 15-SUBSTITUTED 4-AZASTEROIDS MERCK & CO INC (US) 1998-09-16 EP disclosed
EP-0700291-A4 15-SUBSTITUTED 4-AZASTEROIDS MERCK & CO INC (US) 1996-07-03 EP disclosed
EP-0700291-A1 15-SUBSTITUTED 4-AZASTEROIDS MERCK & CO. INC. (US) 1996-03-13 EP disclosed
US-5359071-A Selective antagonist of testosterone 5-alpha-reductase 1 MERCK & CO., INC. (US) 1994-10-25 US disclosed
WO-1994020104-A1 15-SUBSTITUTED 4-AZASTEROIDS MERCK & CO, INC. (US) 1994-09-15 WO disclosed
US-4656233-A \"Living\" polymers and chain transfer-regulated polymerization process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-07 US disclosed
EP-0186330-A1 \"Living\" polymers and chain transfer-regulated polymerization process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-02 EP disclosed
EP-0021883-A2 N-acyl-amino acid derivatives and pharmaceutical compositions containing them, intermediates and starting compounds MERRELL TORAUDE ET COMPAGNIE (FR) 1981-01-07 EP disclosed