SCHEMBL4594959

SCHEMBL4594959

OC(O)O.c1ccc(SC(Sc2ccccc2)Sc2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
MGLL Q99685 1/20 0.43
HSD17B10 Q99714 1/20 0.43
LMNA P02545 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 2/20 0.38
KDM4E B2RXH2 4/20 0.37
GAA P10253 2/20 0.37
PKM P14618 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2C P18825 1/20 0.36
FFAR1 O14842 1/20 0.36
HIF1A Q16665 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1713865 0.91 SMN1; SMN2 (0.50) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL95522 0.81 LMNA (0.42) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL5081592 0.77 LMNA (0.40) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL15912538 0.77 KDM4E (0.41) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL1226276 0.76 SMN1; SMN2 (0.41) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL343269 0.74 SMN1; SMN2 (0.45) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL5173197 0.74 SMN1; SMN2 (0.45) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL1453001 0.74 SMN1; SMN2 (0.45) SMN1; SMN2MAPTHPGDMGLLHSD17B10
SCHEMBL23414339 0.74 LMNA (0.38) SMN1; SMN2MAPTHPGDMGLLHSD17B10
Fluoride SCHEMBL1336886 0.72 MAOA (0.48) SMN1; SMN2MAPTHPGDMGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080220288-A1 Light-Emitting Device, And Method For The Manufacture Thereof KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-09-11 US disclosed
EP-1927145-A2 LIGHT-EMITTING DEVICE, AND METHOD FOR THE MANUFACTURE THEREOF Koninklijke Philips Electronics N.V. (NL) 2008-06-04 EP disclosed
WO-2007031923-A2 LIGHT-EMITTING DEVICE, AND METHOD FOR THE MANUFACTURE THEREOF KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-03-22 WO disclosed