SCHEMBL171413

SCHEMBL171413

COC(=O)c1cc(C)n[nH]1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.67
ALPL P05186 11/20 0.58
MAPT P10636 6/20 0.58
RAB9A P51151 3/20 0.58
POLB P06746 2/20 0.58
GAA P10253 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 2/20 0.53
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.47
HTT P42858 1/20 0.46
GFER P55789 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28813265 0.88 MAPK1 (0.54) MAPK1ALPLMAPTRAB9APOLB
SCHEMBL970232 0.81 ALPL (0.57) MAPK1ALPLMAPTRAB9AGAA
SCHEMBL285996 0.80 MAPK1 (0.67) MAPK1ALPLMAPTRAB9APOLB
SCHEMBL68056 0.80 MAPK1 (1.00) MAPK1ALPLMAPTRAB9APOLB
Hydrochloric Acid SCHEMBL28348020 0.79 ALPL (0.56) MAPK1ALPLMAPTRAB9AGAA
SCHEMBL30614240 0.78 MAPK1 (0.96) MAPK1ALPLMAPTRAB9APOLB
SCHEMBL21630583 0.78 MAPK1 (0.65) MAPK1ALPLMAPTRAB9APOLB
SCHEMBL20517628 0.78 MAPK1 (0.65) MAPK1ALPLMAPTRAB9APOLB
SCHEMBL286531 0.78 MAPK1 (0.65) MAPK1ALPLMAPTRAB9APOLB
SCHEMBL30107039 0.78 MAPK1 (0.70) MAPK1ALPLMAPTRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103880749-B A kind of chemical synthesis process of 3- methyl -5- pyrazole carboxylic acid methyl esters 南通大学 2019-01-01 CN claimed
CN-103880749-A Chemical synthesis method of methyl 3-methyl-5-pyrazolylformate UNIV NANTONG 2014-06-25 CN claimed
EP-4735433-A2 SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF Viva Star Biosciences (US) Inc. (US) 2026-05-06 EP disclosed
US-20260070924-A1 INDAZOLE MACROCYCLES AND THEIR USE BLOSSOMHILL THERAPEUTICS INC (US) 2026-03-12 US disclosed
EP-4705308-A1 EGFR INHIBITORS FOR TREATING DISEASE Blossomhill Therapeutics, Inc. (US) 2026-03-11 EP disclosed
EP-4562015-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
EP-4536225-A1 INDAZOLE MACROCYCLES AND THEIR USE Blossomhill Therapeutics, Inc. (US) 2025-04-16 EP disclosed
EP-4526298-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS F. Hoffmann-La Roche AG (CH) 2025-03-26 EP disclosed
US-20250074913-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS HOFFMANN-LA ROCHE INC. (US) 2025-03-06 US disclosed
CN-119325379-A Indazole macrocyclic compounds and uses thereof 荣山医药股份有限公司 2025-01-17 CN disclosed
WO-2025006681-A2 SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF VIVA STAR BIOSCIENCES (US) INC. (US) 2025-01-02 WO disclosed
US-20040058281-A1 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2004-03-25 US disclosed
CN-1432608-A Aldehyde deodorant composition and aldehyde deodorant coating material OTSUKA KAGAKU KK (JP) 2003-07-30 CN disclosed
US-6524781-B2 Mixture of photosensitive silve rhalide emulsion, organic silver compound and reducing agent; controlling odors KONICA CORPORATION (JP) 2003-02-25 US disclosed
CN-1387445-A aldehyde deodorant composition OSHIKA SHINKO CO (JP) 2002-12-25 CN disclosed
CN-1378462-A deodorant composition OTSUKA KAGAKU KK (JP) 2002-11-06 CN disclosed
US-20020012888-A1 Photothermographic material KONICA CORPORATION, A CORPORATION OF JAPAN (JP) 2002-01-31 US disclosed
US-5859007-A TREATMENT OF DIABETES, OBESITY GLAXO WELLCOME INC. (US) 1999-01-12 US disclosed
EP-0755384-A1 CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES GLAXO WELLCOME INC. (US) 1997-01-29 EP disclosed
WO-1995028391-A1 CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES GLAXO WELLCOME INC. (US) 1995-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070924-A1 INDAZOLE MACROCYCLES AND THEIR USE NR0B2, NR0B1, ESRRA MAPK1 3437/4885ALPL 3097/4885MAPT 3932/4885
US-20250074913-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS STING1, CGAS, MAVS MAPK1 1071/4885ALPL 4759/4885MAPT 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.