SCHEMBL17142190

SCHEMBL17142190

CCCCCC(N)Nc1ccc2c(=O)[nH][nH]c(=O)c2c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ CHEK1 O14757 1/20 0.35
▸ BRD4 O60885 2/20 0.34
▸ SPHK1 Q9NYA1 5/20 0.34
▸ SPHK2 Q9NRA0 1/20 0.34
▸ PARP1 P09874 1/20 0.33
▸ PIK3CD O00329 1/20 0.32
▸ DAO P14920 1/20 0.32
▸ AR P10275 1/20 0.31
▸ PARP15 Q460N3 3/20 0.31
▸ PARP10 Q53GL7 2/20 0.31
▸ PARP3 Q9Y6F1 1/20 0.31
▸ SGK1 O00141 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17142241 0.90 KDM4E (0.38) KDM4ETDP1CHEK1BRD4PIK3CD
SCHEMBL6263855 0.81 KDM4E (0.37) KDM4ETDP1CHEK1BRD4PIK3CD
SCHEMBL17142230 0.76 KDM4E (0.43) KDM4ETDP1PIK3CDDAOAR
SCHEMBL3683020 0.76 KDM4E (0.45) KDM4ETDP1PIK3CDPARP15PARP10
SCHEMBL8755820 0.75 KDM4E (0.47) KDM4ETDP1PIK3CDPARP15PARP10
SCHEMBL4300271 0.73 KDM4E (0.39) KDM4ETDP1PIK3CDARPARP15
SCHEMBL5179312 0.73 PIK3CD (0.40) KDM4ETDP1CHEK1BRD4PIK3CD
SCHEMBL17142193 0.71 KDM4E (0.50) KDM4ETDP1PARP1DAOAR
SCHEMBL17142184 0.70 KDM4E (0.51) KDM4ETDP1PARP1DAOAR
SCHEMBL28766902 0.70 CSNK1E (0.45) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129783-B1 USE OF ABSORBENT PARTICLES FOR IMPROVING SIGNAL DETECTION IN AN ANALYSIS METHOD BIO RAD EUROPE GMBH (CH) 2021-06-02 — — EP disclosed
EP-3129782-B1 CONTROL MARKER FOR IMPLEMENTING METHODS OF ANALYSIS ON SPOTS BIO RAD EUROPE GMBH (CH) 2021-01-06 — — EP disclosed
EP-3129783-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129782-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129784-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3126832-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS Bio-Rad Innovations (FR) 2017-02-08 — — EP disclosed
WO-2015155255-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155248-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155254-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015150583-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS BIO-RAD INNOVATIONS (FR) 2015-10-08 — — WO disclosed
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