SCHEMBL17142241

SCHEMBL17142241

CCCC(N)Nc1ccc2c(=O)[nH][nH]c(=O)c2c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.38
▸ TDP1 Q9NUW8 1/20 0.36
▸ PARP15 Q460N3 9/20 0.33
▸ PARP10 Q53GL7 6/20 0.33
▸ BRD4 O60885 2/20 0.33
▸ PARP3 Q9Y6F1 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ CHEK1 O14757 1/20 0.32
▸ PIK3CD O00329 1/20 0.32
▸ BRAF P15056 1/20 0.31
▸ ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17142190 0.90 KDM4E (0.37) KDM4ETDP1PARP15PARP10BRD4
SCHEMBL17142230 0.80 KDM4E (0.43) KDM4ETDP1PARP15PARP10HSD17B10
SCHEMBL5179312 0.79 PIK3CD (0.40) KDM4ETDP1PARP15PARP10BRD4
SCHEMBL6263855 0.78 KDM4E (0.37) KDM4ETDP1PARP15PARP10BRD4
SCHEMBL4300271 0.77 KDM4E (0.39) KDM4ETDP1PARP15PARP10PARP3
SCHEMBL3683020 0.73 KDM4E (0.45) KDM4ETDP1PARP15PARP10PARP3
SCHEMBL4300524 0.72 KDM4E (0.47) KDM4ETDP1PARP15PARP10PARP3
SCHEMBL8755820 0.72 KDM4E (0.47) KDM4ETDP1PARP15PARP10PARP3
SCHEMBL3277310 0.70 HSD17B10 (0.46) KDM4ETDP1PARP15PARP10HSD17B10
SCHEMBL5180879 0.69 KDM4E (0.50) KDM4ETDP1PARP15PARP10PARP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129783-B1 USE OF ABSORBENT PARTICLES FOR IMPROVING SIGNAL DETECTION IN AN ANALYSIS METHOD BIO RAD EUROPE GMBH (CH) 2021-06-02 — — EP disclosed
EP-3129782-B1 CONTROL MARKER FOR IMPLEMENTING METHODS OF ANALYSIS ON SPOTS BIO RAD EUROPE GMBH (CH) 2021-01-06 — — EP disclosed
EP-3129783-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129784-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129782-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3126832-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS Bio-Rad Innovations (FR) 2017-02-08 — — EP disclosed
WO-2015155254-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155255-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155248-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015150583-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS BIO-RAD INNOVATIONS (FR) 2015-10-08 — — WO disclosed
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