Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3683020 | 0.86 | KDM4E (0.45) | KDM4ETDP1HSD17B10ALDH1A1TP53 | |
| SCHEMBL4300524 | 0.85 | KDM4E (0.47) | KDM4ETDP1HSD17B10ALDH1A1TP53 | |
| SCHEMBL8755820 | 0.85 | KDM4E (0.47) | KDM4ETDP1HSD17B10ALDH1A1TP53 | |
| SCHEMBL4300271 | 0.84 | KDM4E (0.39) | KDM4ETDP1HSD17B10ALDH1A1TP53 | |
| SCHEMBL17142190 | 0.81 | KDM4E (0.37) | KDM4ETDP1HSD17B10BRD4CHEK1 | |
| SCHEMBL17142241 | 0.78 | KDM4E (0.38) | KDM4ETDP1HSD17B10BRD4CHEK1 | |
| SCHEMBL2722703 | 0.76 | ALDH1A1 (0.60) | KDM4ETDP1HSD17B10ALDH1A1TP53 | |
| SCHEMBL17142230 | 0.75 | KDM4E (0.43) | KDM4ETDP1HSD17B10PIK3CDDAO | |
| SCHEMBL11345753 | 0.72 | ALDH1A1 (0.42) | TDP1HSD17B10ALDH1A1TP53HSP90AA1 | |
| SCHEMBL11442419 | 0.70 | ALDH1A1 (0.58) | KDM4ETDP1HSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1588165-A2 | VITAMIN D ASSAY | Diasorin Inc. (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004063704-A2 | VITAMIN D ASSAY | DIASORIN INC. (US) | 2004-07-29 | — | — | WO | disclosed |