SCHEMBL17142230

SCHEMBL17142230

CC(N)Nc1ccc2c(=O)[nH][nH]c(=O)c2c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.43
▸ HSD17B10 Q99714 1/20 0.37
▸ AR P10275 2/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ PARP15 Q460N3 6/20 0.34
▸ BRAF P15056 2/20 0.34
▸ DAO P14920 3/20 0.33
▸ PARP10 Q53GL7 3/20 0.33
▸ METAP2 P50579 1/20 0.33
▸ PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17142241 0.80 KDM4E (0.38) KDM4EHSD17B10TDP1PARP15BRAF
SCHEMBL4300271 0.80 KDM4E (0.39) KDM4EHSD17B10ARTDP1PARP15
SCHEMBL3683020 0.76 KDM4E (0.45) KDM4EHSD17B10TDP1PARP15PARP10
SCHEMBL17142190 0.76 KDM4E (0.37) KDM4EHSD17B10ARTDP1PARP15
SCHEMBL7070839 0.76 KDM4E (0.50) KDM4EHSD17B10ARTDP1PARP15
SCHEMBL3277310 0.76 HSD17B10 (0.46) KDM4EHSD17B10TDP1PARP15BRAF
SCHEMBL6263855 0.75 KDM4E (0.37) KDM4EHSD17B10ARTDP1PARP15
SCHEMBL4300524 0.75 KDM4E (0.47) KDM4EHSD17B10TDP1PARP15PARP10
SCHEMBL8755820 0.75 KDM4E (0.47) KDM4EHSD17B10TDP1PARP15PARP10
SCHEMBL438637 0.71 AR (0.47) KDM4EHSD17B10ARTDP1PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129783-B1 USE OF ABSORBENT PARTICLES FOR IMPROVING SIGNAL DETECTION IN AN ANALYSIS METHOD BIO RAD EUROPE GMBH (CH) 2021-06-02 — — EP disclosed
EP-3129782-B1 CONTROL MARKER FOR IMPLEMENTING METHODS OF ANALYSIS ON SPOTS BIO RAD EUROPE GMBH (CH) 2021-01-06 — — EP disclosed
EP-3129783-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129784-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129782-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3126832-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS Bio-Rad Innovations (FR) 2017-02-08 — — EP disclosed
WO-2015155248-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155254-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155255-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015150583-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS BIO-RAD INNOVATIONS (FR) 2015-10-08 — — WO disclosed
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