Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99069 | 0.84 | PIK3CA (0.50) | ALDH1A1L3MBTL1LMNAHPGDHSD17B10 | |
| SCHEMBL98783 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2ALOX12ALDH1A1L3MBTL1MAPT | |
| SCHEMBL98984 | 0.77 | PIK3CA (0.49) | SMN1; SMN2ALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL171639 | 0.76 | PAK4 (0.36) | ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL98098 | 0.75 | PIK3CA (0.49) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL96510 | 0.74 | YTHDC1 (0.40) | ALDH1A1MAPTUSP2HPGD | |
| SCHEMBL99695 | 0.74 | MAPT (0.35) | SMN1; SMN2ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL97311 | 0.74 | PDE10A (0.42) | ALDH1A1L3MBTL1LMNATSHRHPGD | |
| SCHEMBL97830 | 0.73 | ALDH1A1 (0.34) | SMN1; SMN2ALOX12ALDH1A1L3MBTL1 | |
| SCHEMBL100087 | 0.72 | PIK3CA (0.46) | ALDH1A1L3MBTL1MAPTLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426130-A1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 2012-03-07 | — | — | EP | disclosed |