Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28410071 | 0.85 | MGAM (0.49) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL15672918 | 0.81 | MGAM (0.51) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL196440 | 0.81 | MGAM (0.55) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL27526791 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL6065171 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL16674078 | 0.77 | CA1 (0.55) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL29496937 | 0.76 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL5463881 | 0.76 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL5702570 | 0.75 | CA1 (0.50) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL29894839 | 0.75 | CA1 (0.50) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015153252-A1 | ANTI-VASCULATURE AND ANTI-TUBULIN COMBRETASTATIN ANALOGS FOR TREATMENT OF CANCER | XAVIER UNIVERSITY OF LOUISIANA (US) | 2015-10-08 | — | — | WO | claimed |