Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HCK | P08631 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17145103 | 0.85 | SMN1; SMN2 (0.48) | MGAMGAASIMGAM2PIK3CD | |
| SCHEMBL2714237 | 0.85 | ALDH1A1 (0.52) | GAASMN1; SMN2ALDH1A1S100A4TDP1 | |
| SCHEMBL15672918 | 0.81 | MGAM (0.51) | MGAMGAASIMGAM2PIK3CD | |
| SCHEMBL23175282 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29625828 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL13732793 | 0.78 | GAA (0.54) | MGAMGAASIMGAM2PIK3CD | |
| SCHEMBL2713912 | 0.77 | S100A4 (0.49) | MTORNPC1RAB9AS100A4L3MBTL1 | |
| SCHEMBL17927356 | 0.76 | ALDH1A1 (0.57) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL30170729 | 0.76 | ALDH1A1 (0.57) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL28417539 | 0.76 | SYK (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320575-B | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-111320575-A | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2020-06-23 | — | — | CN | disclosed |