Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12452306 | 1.00 | PRCP (0.44) | PRCPIDO1PDPK1SRD5A1PIN1 | |
| SCHEMBL802812 | 1.00 | PRCP (0.44) | PRCPIDO1PDPK1SRD5A1PIN1 | |
| SCHEMBL9456547 | 0.85 | PRCP (0.42) | PRCPIDO1PDPK1SRD5A1PIN1 | |
| SCHEMBL10283336 | 0.83 | OPRM1 (0.41) | PRCPSIGMAR1 | |
| SCHEMBL20476267 | 0.82 | PIN1 (0.42) | PRCPPDPK1SRD5A1PIN1 | |
| SCHEMBL12452034 | 0.78 | CYP19A1 (0.46) | SIGMAR1 | |
| SCHEMBL12452014 | 0.77 | DRD2 (0.47) | IDO1PDPK1SRD5A1PIN1CYP11B2 | |
| SCHEMBL20662893 | 0.77 | PRCP (0.47) | PRCPIDO1PDPK1SRD5A1SIGMAR1 | |
| SCHEMBL14065441 | 0.77 | IDO1 (0.46) | IDO1PDPK1SRD5A1PIN1SIGMAR1 | |
| SCHEMBL10283375 | 0.77 | DRD2 (0.47) | IDO1PDPK1SRD5A1PIN1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150525-B2 | Heteroaryl compounds useful as inhibitors of E1 activating enzymes | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-10-06 | — | — | US | disclosed |